Sitc 2025 Ak132 . Working at SITC Container Lines Malaysia Sdn Bhd Company Profile A similar approach is being pursued by Akeso, which in addition to the MAb ligufalimab recently took into phase 1 AK132, an anti-Claudin18.2 x CD47 MAb And it's worth remembering Shattuck Labs, whose own take on CD47 differs by the inclusion of a CD40L domain to activate macrophages; further data from early trials of SL-154 are due this year.
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Cellular Therapy for Solid Tumors March 12-14, 2025 in San Diego, CA at Rancho Bernardo Inn or Virtually The binding activity of AK132, anti-CLDN18.2 and AK117 to CHO-K1 cells which transfected with CLDN18.2 and CD47 were detected by FACS
Sitc 2025 Annual Meeting Benni Kristine Results AK132 could bind to human CD47 and CLDN18.2 on CD47 + CLDN18.2 + cells, with same activity relative to its parental mAbs, AK117 (anti-CD47 mAb) and anti-CLDN18.2 The SITC Spring Scientific, Cellular Therapy for Solid Tumors, will address the recent advances in adoptive cellular therapy for solid tumors and rate-limiti. The binding activity of AK132, anti-CLDN18.2 and AK117 to CHO-K1 cells which transfected with CLDN18.2 and CD47 were detected by FACS
Source: ucaulsanmtb.pages.dev Global Immunotherapy Access Society for Immunotherapy of Cancer (SITC) , The 2025 SITC Spring Scientific, Cellular Therapy for Solid Tumors, will address the recent advances in adoptive cellular therapy for solid tumors and rate-limiting challenges that impede bringing these novel therapies to patients in need. Most importantly, AK132 neither bound to RBCs nor had ADCC or ADCP effects on RBCs
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Source: aastxtrxesp.pages.dev Sitc 2024 Ak1320 Elyn Norene , AK132 efficiently inhibits tumor growth in mice with subcutaneous MC38-hCD47hCLDN18.2 tumor. Results AK132 could bind to human CD47 and CLDN18.2 on CD47 + CLDN18.2 + cells, with same activity relative to its parental mAbs, AK117 (anti-CD47 mAb) and anti-CLDN18.2
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SITC 2023 Poster 549 . The Women in Cancer Immunotherapy Network (WIN) is a SITC initiative seeking to promote and elevate women in the cancer immunotherapy field The binding activity of AK132, anti-CLDN18.2 and AK117 to CHO-K1 cells which transfected with CLDN18.2 and CD47 were detected by FACS